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Generic Name: ESTRADIOL Chemical Name: ESTRADIOL (es-tra-DYE-ol) Common Uses of Esclim This medicine is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, and to treat other conditions as determined by your doctor. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medicines (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well, and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options. Possible Esclim Side Effects Side effects that may go away during treatment, include dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, breast tenderness, or skin redness/irritation at the application site. If they continue or are bothersome, check with your doctor. Contact your doctor immediately if you experience mental/mood changes (e.g., severe depression, memory loss), calf/pain swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands/feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding, or prolonged bleeding), unusual vaginal discharge/itching/odor, or yellowing of the eyes/skin. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. General CautionsKeep all doctor and laboratory appointments while you are using this medicine. You should have a complete physical examination, including blood pressure measurements, breast and pelvic examinations, and a pap test (for vaginal cancer), at least once a year. You should also have periodic mammograms as determined by your doctor. Follow your doctor's instructions for examining your own breasts, and report any lumps immediately. This medicine may alter certain lab results. Make sure laboratory personnel and your doctors know that you are using this medicine. If you will be having surgery or will be confined to a chair or bed for a long period of time (e.g., a long plane flight), notify your doctor beforehand. Special precautions may need to be taken in these circumstances while you are taking this medicine. This medicine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. Limit alcoholic beverages while using this medicine. This medicine may cause a patchy darkening of the skin on the face (melasma). Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding use of sunscreens and protective clothing. Cigarette smoking can increase the chance of blood clots while taking this medicine (especially in women over the age of 35). Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. Caution is advised when using this medicine in children as it might stunt their growth. If used in children, their growth pattern should be monitored. For Women: this medicine has been shown to cause harm to the human fetus. Do not use this medicine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if this medicine is excreted in breast milk. If you are or will be breast-feeding while taking this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
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