Animal care and service workers who witness abused animals or who assist in the euthanizing of unwanted, aged, or hopelessly injured animals may experience emotional stress. Those working for private humane societies and municipal animal shelters often deal with the public, some of whom might react with hostility to any implication that the owners are neglecting or abusing their pets. Such workers must maintain a calm and professional demeanor while they enforce the laws regarding animal care.

Animal care and service workers may work outdoors in all kinds of weather. Hours are irregular. Animals must be fed every day, so caretakers often work weekend and holiday shifts. In some animal hospitals, research facilities, and animal shelters, an attendant is on duty 24 hours a day, which means night shifts.