Because technologists and technicians are on their feet for long periods and may lift or turn disabled patients, physical stamina is important. Technologists and technicians work at diagnostic machines, but may also perform some procedures at patients' bedsides. Some travel to patients in large vans equipped with sophisticated diagnostic equipment.

Although radiation hazards exist in this occupation, they are minimized by the use of lead aprons, gloves, and other shielding devices, as well as by instruments monitoring radiation exposure. Technologists and technicians wear badges measuring radiation levels in the radiation area, and detailed records are kept on their cumulative lifetime dose.