Within the Federal government, most jobs are as Occupational Safety and Health Administration (OSHA) inspectors, who enforce U.S. Department of Labor regulations that ensure adequate safety principles, practices, and techniques are applied in workplaces. Employers may be fined for violation of OSHA standards. Within the U.S. Department of Health and Human Services, occupational health and safety specialists working for the National Institute of Occupational Safety and Health (NIOSH) provide private companies with an avenue to evaluate the health and safety of their employees without the risk of being fined. Most large government agencies also employ occupational health and safety specialists and technicians who work to protect agency employees.

Most private companies either employ their own occupational health and safety personnel or contract with occupational health and safety professionals to ensure OSHA compliance.